Alexander County Vacation Packages

Book a Hotel + Flight or Car together to unlock savings

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  • Plan, book, travel with confidence

  • Better together

    Save up to CA $4,200 when you book a flight and hotel together*

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    With over 300,000 hotels worldwide, it's easy to create a perfect package

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Your Alexander County Vacation

Embark on your next epic adventure with an Alexander County vacation package, and leave relaxed knowing the finer details are organized. And with the ability to tailor your escape, you know it'll be one to remember. Start your trip to Alexander County by spending a few days in Cairo, one of the best cities here. Whether you're planning to travel on a shoestring or in the lap of luxury, Expedia are here to help you tailor-make your next dream Alexander County vacation.

Top vacation destinations in Alexander County

A steel bridge with a sunset in the background.
FlightsFlightsHotelsHotels

Cairo

Cairo

Alexander County Hotel Deals

Peaceful secluded cabin located near Horseshoe Lake

Peaceful secluded cabin located near Horseshoe Lake

Miller City IL
The price is CA $177 per night from Jul 7 to Jul 8
CA $177
CA $283 total
Jul 7 - Jul 8
includes taxes & fees
Peaceful secluded cabin located near Horseshoe Lake
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive Cape Girardeau MO
Fully refundableReserve now, pay when you stay
The price is CA $156 per night from Jul 26 to Jul 27
CA $156
CA $176 total
Jul 26 - Jul 27
includes taxes & fees
9.6/10 Exceptional! (1,003 reviews)
"We loved it and will look for this Brand again! It was safe and clean and perfect for an overnight stay."

Reviewed on Jul 3, 2026

Drury Plaza Hotel Cape Girardeau Conference Center
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner Sikeston MO
Fully refundableReserve now, pay when you stay
The price is CA $157 per night from Jul 14 to Jul 15
CA $157
CA $181 total
Jul 14 - Jul 15
includes taxes & fees
9.6/10 Exceptional! (1,002 reviews)
"Very clean"

Reviewed on Jul 1, 2026

Drury Inn & Suites Sikeston, MO
See all 218 properties in Alexander County
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Family Vacations
Family Vacations

Frequently asked questions

How much does an Alexander County vacation package cost?
Maybe less than you might think — from as low as , actually! By combining hotels, flights and car rentals into your own tailor-made vacation package, your getaway to Alexander County is only clicks away.
How do I get a cheap travel package to Alexander County?
Our Alexander County vacation packages promise plenty of savings for the savvy wanderer. For the best deal, simply combine your flights, hotels and rental cars into a convenient package. But great bargains are just the beginning of your next unforgettable adventure. When you book with Expedia, you'll have more than 550 airlines and 1,000,000 hotel options globally to select from. Whatever your style or budget, there's a vacation package here just for you.
What are the top hotels in Alexander County?
If you're headed to Tamms, you can't go wrong with Quality Inn Cairo I-57 and Beautiful Cabin Retreat. Both are great bases for discovering this unique Alexander County city.
How far in advance should I book my Alexander County vacation?
Reserving your flights early with Expedia means one less thing to worry about. Many air carriers advertise prices up to 12 months prior to departure dates. Typically, this is the cheapest time to book. If circumstances have left you booking late, incredible deals to Alexander County sometimes emerge just a few weeks before departure.
What does an Expedia Alexander County travel package include?
Flights, hotels and a cool car for all your road trip adventures. Simply choose your favorite bundle and gain access to great discounts. Once you've made your booking, add on some tours and experiences and watch your savings grow. When it comes to creating your Alexander County getaway, you're in control!
What should I know before booking an Alexander County travel package?
Get set to save with an Expedia travel package. Combine your airfares, rental cars and hotels and score fabulous discounts. You're not limited to hotels, however. Book with us and choose from beachfront villas, chalets in the middle of mountains and even houseboats and castles!
Can I choose my airline with an Alexander County Expedia vacation package?
Yes — and it's simple too. Expedia has access to more than 550 partner airlines worldwide. Our vacation packages give you the flexibility to take your pick of available flights, hotels and activities that suit you.
If I'm not able to travel, can I cancel my Alexander County vacation package?
You can. We totally understand that life happens, so we're happy to help if you have to make changes to your Alexander County vacation package. You may be able to cancel or change your itinerary for free if you've booked within 24 hours. Your hotel, airline or car rental company may impose a fee if you booked more than 24 hours ago. Take a look at our Customer Service Portal for further information. Also, check your itinerary for the nitty-gritty on change fees.

Stay near popular Alexander County attractions

Fort Defiance State Park

7.4/10 (15 reviews)
You can take time to visit Fort Defiance State Park during your travels to Cairo. Stroll along the riverfront or visit the churches while you're in the area.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.